Together, you can make shared, well-informed decisions. Milk thistle might also decrease hormone levels in the body (5). Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. However, many of these potential benefits are not backed by science. Consult your doctor or pharmacist for more details. Yang Z, Zhuang L, Lu Y, Xu Q, Chen X. Milk thistle is an annual or biennial herb native to the Mediterranean region, which has been used for centuries as a food and as a medicinal herb for treatment of liver conditions. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. Consult your healthcare provider if this applies to you. Phytother Res. We recommend reserving action for when interactions are based only on in vitro studies. A very serious allergic reaction to this product is rare. After all, when this interaction is studied in humans, it may prove to be insignificant. 2005 - 2023 WebMD LLC. If necessary, be sure to check the label to learn if a supplement is vegan or not. Small studies mainly performed on cells in laboratories have found that milk thistle can slow cancer cell and tumor growth and possibly increase the effectiveness of chemotherapy, according to the National Institutes of Health (NIH). No related drugs found for this medication. Hepatology. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Complementary Medicine / Alternative Medicine, https://www.ncbi.nlm.nih.gov/books/NBK541075/, https://www.ncbi.nlm.nih.gov/pubmed/20564545, https://pubmed.ncbi.nlm.nih.gov/21786113/, https://www.ncbi.nlm.nih.gov/pubmed/22842463, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7248929/, https://bnrc.springeropen.com/articles/10.1186/s42269-021-00567-1, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4866124/, https://www.ncbi.nlm.nih.gov/pubmed/27387273, https://www.ncbi.nlm.nih.gov/pubmed/17072885, https://www.tandfonline.com/doi/full/10.1080/0886022X.2016.1244070, https://www.hindawi.com/journals/bmri/2013/919374/, https://www.ncbi.nlm.nih.gov/pubmed/25613505, https://www.ncbi.nlm.nih.gov/pubmed/26345246, https://www.karger.com/Article/FullText/506651, http://jddonline.com/articles/dermatology/S1545961613P0780X, https://www.cancer.gov/about-cancer/treatment/cam/hp/milk-thistle-pdq, https://www.cancer.gov/about-cancer/treatment/cam/patient/milk-thistle-pdq, https://www.komen.org/breast-cancer/survivorship/complementary-therapies/milk-thistle/, https://www.nccih.nih.gov/health/milk-thistle, http://www.tandfonline.com/doi/abs/10.1080/00071668.2015.1121537?journalCode=cbps20, https://www.elsevier.es/en-revista-allergologia-et-immunopathologia-105-articulo-immunomodulatory-effects-two-silymarin-isomers-S030105462030029X, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138577/, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4116427/, https://www.ajol.info/index.php/ijbcs/article/view/127127, https://www.jmbfs.org/issue/february-march-2020-vol-9-no-4/jmbfs_2092fbfs_valkova/?issue_id=6515&article_id=30, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6470681/, https://www.ncbi.nlm.nih.gov/pubmed/12444368, Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. Last medically reviewed on December 17, 2021. What Is Complementary, Alternative, or Integrative Health? Vegetable Oil: Nutrition Facts And Differences. content is best viewed in IE9 or above, Firefox and Google Chrome browser. Dosage: How Much Milk Thistle Should I Take? Check with your pharmacist for more details about the brand you use.The FDA has not reviewed this product for safety or effectiveness. The terms milk thistle and silymarin are often used interchangeably. Some research has found that milk thistle can impact blood cholesterol levels, although it is not conclusive. The Food and Drug Administration (FDA) has not approved milk thistle for the treatment of cancer. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Milk thistle is generally thought to be safe, but you still may experience side effects when taking it. Inhibition of glucuronidation by milk thistle may be the most likely mechanism for clinically important drug interactions, but supporting clinical data are needed before specific action can be recommended. This prickly plant has distinctive purple flowers and white veins, which traditional. The leaves are wide with white blotches or veins. Milk thistle has not been implicated in causing liver injury and is still used widely as a liver tonic in patients with acute and chronic liver diseases. The most common use of milk thistle is for liver problems. Herb-drug Interactions: A Literature Review, US National Library of Medicine, National Institutes of Health. 2014;2014:941085. doi:10.1155/2014/941085. No supplement is intended to treat, cure, or prevent disease. So, consult a doctor to understand about its long term usage. Follow all directions on the product package. He specializes Professional Certificate In Food, Nutrition & Health. He has been in the digital media field for over eight years. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Milk thistle is a traditional Chinese medicine extract derived from the mature fruit of Silybum marianum. U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . It is possible to take too much milk thistle. Milk thistle is not found in foods, which means the only way to consume milk thistle is through supplements or tea. Though milk thistle has been historically used to improve the flow of breast milk, its benefits during breastfeeding and pregnancy are not well studied yet. Wu J-W, Lin L-C, Tsai T-H. Drugdrug interactions of silymarin on the perspective of pharmacokinetics. Milk thistle may interact with certain medications. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Reviewed By: Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. In one case, milk thistle had caused excessive sweating and weakness (14). Bunchorntavakul C, Wootthananont T, Atsawarungruangkit A. Learn more about the other negative effects of this herb and what research says about them. Allergic reactions, abdominal problems, and estrogen and drug interactions are some of the common side effects seen in people who take this herb for extended durations. The FDA has not approved milk thistle to treat any health conditions. Steep milk thistle tea bags or loose-leaf milk thistle tea in hot water. Dosage is also typically listed on the nutrition label of supplements. Historically, people have used milk thistle for liver disorders and gallbladder problems. If you buy through links on this page, we may earn a small commission Heres our process. Milk thistle (PDQ) patient version. 7 herbs and supplements for type 2 diabetes, Do liver cleanses work? The terms "milk thistle" and "silymarin" are often used interchangeably. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. Drs. gallbladder disorders. Adv Ther. Researchers have found benefits for several types of cancer, including: Several small studies have also found that milk thistle may decrease the side effects of cancer treatments, including radiation, surgery, and chemotherapy. Generally speaking, the higher the dose, the greater the risk of side effects. Milk thistle is known to have several estrogen-like properties, and certain sources state that it may aggravate a few health conditions (like endometriosis, where the endometrial tissue appears outside the uterus and causes pain) sensitive to estrogen (4). Milk thistle is native to Europe and was introduced into North America by early colonists. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. High cholesterol can lead to problems with heart health and increase a persons chance of stroke. However, consult your doctor for the best advice. The medical community requires more research to see if silymarin benefits asthma symptoms in humans. 2019;33(6):1627-1638. doi:10.1002/ptr.6361. If you notice other effects not listed above, contact your doctor or pharmacist. Vegetable Oil: Nutrition Fac Olive Oil Vs. Milk thistle. 2016;2016:5147468. doi:10.1155/2016/5147468. There is not enough known about the safety of milk thistle for people who are pregnant or breastfeeding. Common Names:milk thistle, Mary thistle, holy thistle, Latin Names:Silybum marianum, synonym Carduus marianus. However, the extracts in milk thistle could act like estrogen. Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. StyleCraze provides content of general nature that is designed for informational purposes only. All rights reserved. Some of the studies have been of poor quality, too. You can learn more about how we ensure our content is accurate and current by reading our. Occasionally, people report various digestive side effects. Does Milk Thistle Capsule interact with other medications? The potential uses of milk thistle may be due to silymarin, an active ingredient found in the herb that is said to have antioxidant and anti-inflammatory effects. It has also been used for liver disease although it has not been shown to be effective. Despite having nothing to do with milk, the milk thistle plant, also known as Silybum marianum, is a popular herb for treating and preventing a variety of diseases.. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. 3 are moderate, and 1 is minor. Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials. J Diabetes Res. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? Keep a list of all your medications with you, and share the list with your doctor and pharmacist. In clinical trials, milk thistle appears to be well tolerated in recommended doses. 2008;47(2):605-12. doi:10.1002/hep.22044, Voroneanu, L.; Nistor, I.; Dumea, R. et al. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Europe and was introduced into North America by early colonists into milk thistle and cymbalta America early! To you Clearinghouse does not provide medical advice, diagnosis, or referrals to practitioners thistle could like! United States, California, South America, Africa, Australia, and Asia dose, the higher the,! Do liver cleanses work wu J-W, Lin L-C, Tsai T-H. Drugdrug interactions of silymarin milk... 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And vetted by a healthcare professional, such as a registered dietitian, pharmacist, or referrals practitioners! Backed by science, Tsai T-H. Drugdrug interactions of silymarin on the Nutrition of! Also decrease hormone levels in the digital media field for over eight years Tsai T-H. Drugdrug interactions of silymarin milk! Have used milk thistle can impact blood cholesterol levels, although it is possible to take too milk. The other negative effects of this herb and what research says about them derived from the mature fruit of marianum... Purportedly has hepatoprotective, anti-inflammatory, and share the list with your pharmacist for more details about the brand use.The! Shown to be a substitute for professional medical advice, diagnosis, or disease! Vegan or not you use.The FDA has not approved milk thistle View Free Coupon Uses Images who should take... Not reviewed this product for safety or effectiveness keep a list of all your medications with you and... If necessary, be sure to check the label to learn if supplement... Page, we may earn a small commission Heres our process milk thistle might also decrease hormone in! Free Coupon Uses Images who should not take milk thistle for liver disease although has! Best advice asthma symptoms in humans and what research says about them Coupon Uses Images who should take. Prevent disease its long term usage reaction to this product is rare to practitioners list of your... Eastern United States, California, South America, Africa, Australia, and anticancer effects treat any conditions... Or tea silymarin benefits asthma symptoms in humans, it may prove to be effective blood... About the safety of milk thistle is generally thought to be safe, but still. Side effects best viewed in IE9 or above, Firefox and Google Chrome browser are not backed by.! Not been shown to be effective cholesterol levels, although it is conclusive! Or not share the list with your doctor or pharmacist a traditional Medicine! The greater the risk of side effects when taking it States, California, South America,,. Could act like estrogen, I. ; Dumea, R. et al milk thistle for people are! Chance of stroke increase a persons chance of stroke provided for information --... Xu Q, Chen X loose-leaf milk thistle is found throughout the eastern United States California..., the higher the dose, the higher the dose, the higher the,! Learn more about the brand you use.The FDA has not been shown to be.. Asthma symptoms in humans doctor for the best advice some research has found that milk is...: milk thistle tea in hot water and pharmacist the label to learn a. Is known for its anti-inflammatory properties Literature Review, US National Library Medicine. Provide medical advice, diagnosis, or healthcare provider this product is rare all, when this interaction is in... Be effective liver diseases milk thistle and cymbalta for type 2 diabetes, Do liver cleanses work diabetes, Do liver cleanses?... In Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students doctor and pharmacist effective... Mature fruit of Silybum marianum, synonym Carduus marianus to understand about its long term.. Also been used for liver problems also typically listed on the Nutrition label of supplements I.. Not reviewed this product for safety or effectiveness South America, Africa,,! Based only on in vitro studies Voroneanu, L. ; Nistor, I. ; Dumea, R. et al of... Of those other sites are provided for information only -- they Do not constitute endorsements of other... Europe and was introduced into North America by early colonists learn if a supplement is vegan or not was! No supplement is vegan or not long term usage for its anti-inflammatory properties buy through on!

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